Launch Complex 14 is one of the more historically important complexes at Cape Canaveral Air Force Station. Constructed in 1956 it was dedicated to the developing Atlas program. The first ICBM (Intercontinental Ballistic Missile) developed by the United States—the SM-65 Atlas—was launched from LC14 on June 11, 1957.

On February 20, 1962 Mercury-Atlas 6 launched John Glenn into orbit from Launch Complex 14. This was the first American astronaut to orbit the earth. Three other Mercury launches went from LC14.

In the third man-in-space program—Gemini—Launch Complex 14 was used to launch the Atlas-Agena. This unmanned orbital target vehicle was used by the astronauts in the Gemini spacecraft to practice rendezvous and docking in orbit.